Leading treatment for peritoneal carcinomatosis

HIPEC: intraperitoneal hyperthermic chemotherapy after cytoreduction.

If you have been diagnosed with peritoneal metastases, you probably feel that your options are running out. You need a strategy that goes beyond conventional treatments.

At Peritoneal Cancer Institutewe apply the binomial of cytoreductive surgery (CRS) + HIPECthe most advanced technique in the treatment of peritoneal carcinomatosis. Cytoreductive surgery is used to eliminate the macroscopic tumor and the HIPEC to treat the microscopic tumor residue in a single surgical time.

No commitment.

Image of Dr. Domenico Sabia concentrating on an operation.

What is HIPEC and why is it combined with cytoreduction?

Combined treatment of oncological surgery

To understand what HIPEC is it is necessary to understand that it is not an isolated treatment. The protocol consists of a combination of cytoreductive surgery (CRS) + hyperthermic intraperitoneal cytoreductive surgery (CRS) + hyperthermic intraperitoneal chemotherapy (HIPEC)..

The HIPEC therapy consists of the application of chemotherapy associated with hyperthermia (heat) directly to the abdomen during surgery. But for this to work, a cytoreduction must first be performed. cytoreduction to remove all the visible tumor.

This precision medicine strategy allows the drug to penetrate directly into the tissues affected by peritoneal cancer. peritoneal cancerThis allows the drug to penetrate directly into the tissues affected by peritoneal cancer, both by direct contact of the chemotherapeutics and by opening the cellular pores thanks to heat, which allows drug concentrations impossible to achieve through traditional intravenous routes and a depth of penetration into the tissues of up to 3 mm.

Exclusive specialization in the CRS + HIPEC technique.

Why choose Peritoneal Cancer Institute

Many types of cancer are treated in medical oncology units. At Peritoneal Cancer Institutewe are dedicated only to peritoneal pathology. Thanks to our experience and precision techniques, our patients always receive the most specialized care.

  • Accumulated experience: We perform the procedure CRS + HIPEC with a large annual case volume that guarantees maximum surgical specialty and safety.
  • Sugarbaker Protocol: We follow the international standards of the CRS + HIPEC technique to ensure complete cytoreduction.
  • Reference in HIPEC: National and international patients rely on our unit for highly complex cases.

HIPEC Treatment at Peritoneal Cancer Institute

A high performance center dedicated to you

Peritoneal Cancer Institute performs its interventions at the facilities of the Teknon Medical Center of the Quirónsalud Quirónsalud Group’s Teknon Medical Centera hospital environment of international excellence. Here, our philosophy is focused on personalized medicine: we do not treat diseases, we treat people, with a team dedicated to your physical and emotional recovery.

For whom is cytoreduction + HIPEC effective?

A customized solution for your case

Not all cases of abdominal cancer with peritoneal carcinomatosis are suitable for cytoreduction surgery (CRS) with HIPECEC. cytoreduction surgery (CRS) with HIPEC.. Selection is based on the origin of the disease itself and tumor extent:

Ovarian cancer

Fundamental both in the front line and in relapses.

When the peritoneal surface is affected.

It is the definitive treatment of choice.

Gold-standard treatment

In very selected cases under strict inclusion criteria.

To determine if your case has any therapeutic option, we perform a thorough assessment of your medical history, imaging tests and general health.

Phases of cytoreduction + HIPEC

The surgical rigor of PCI step by step

The CRS + HIPEC is a highly complex procedure that we divide into three distinct phases. three distinct phases to ensure patient safety.

Cytoreduction phase (CRS)

We remove the affected peritoneum and involved organs to leave the abdominal cavity “clean” of visible disease.

Hyperthermic Perfusion Phase

We introduce the chemotherapeutics at controlled temperature (42ºC). Heat enhances the effect of the chemotherapyeradicating microscopic foci.

Washing and sealing

The drug is removed, the abdominal cavity is checked for a final check and drains are placed prior to closure.

Leaders in surgery + HIPEC

Meet our medical team

The PCI team PCI TEAMteam, led by internationally renowned specialists linked to the Centro Médico Teknon – Grupo Quirónsaludhas decades of experience in the treatment of peritoneal metastases.

Our surgeons do not only perform diagnosis, therapeutic approach or precision surgical technique. They research and publish scientific advances that today are applied all over the world. But, above all, they are professionals who will accompany you at all times during and after the during and after the process.

Dr. Domenico Sabia

Director, Peritoneal Cancer Institute.
Medical Director, Peritoneal Oncological Surgery Unit,
Teknon Medical Center

Dr. Lana Bijelic

Co–director, Peritoneal Cancer Institute
Chief, Peritoneal Surface Malignancies Unit, Consorci Sanitary Integral

Dr. Capdevila

Clinical Oncologist

Survival and quality of life with CRS + HIPEC treatment.

Towards disease eradication

The use of HIPEC in peritoneal carcinomatosis has transformed the prognosis of thousands of patients. Scientific evidence shows that cytoreduction + HIPEC significantly improves disease-free survival compared to systemic chemotherapy alone.

Our goal at PCI is not only to treat peritoneal metastases and advanced abdomino-pelvic cancers, but to change the course of the disease and ensure a good quality of life. quality of life.

Testimonials and ratings after HIPEC

Beyond statistics

Frequently asked questions about cytoreduction and HIPEC

Is hot chemotherapy safe?

Yes. Because it is applied locally, systemic absorption is minimal, which reduces typical side effects. reduces the typical side effects of traditional chemotherapy. of traditional chemotherapy.

Depending on the extent of the procedure, the procedure may last from 8 to 12 hours. between 8 and 12 hours. It is a major surgery that requires a dedicated multidisciplinary team.

PCI is the reference center for patients for patients looking for the maximum specialization in the binomial CRS + HIPECattending cases at national and international level.

No, to understand what is HIPEC it is necessary to understand that it is not an isolated treatment. The protocol is a combined combined technique. For hyperthermic chemotherapy to work properly, a complete cytoreduction that removes all of the gross tumor must first be performed.

The main difference is the route of administration and concentration. While traditional chemotherapy travels via the systemic route, the HIPEC is a precision medicine strategy that penetrates directly penetrates directly into the tissues of the abdominal cavity and especially into the cancer cells. This makes it possible to achieve drug concentrations far superior to those that would be impossible to achieve by traditional intravenous route.

Generally, systemic side systemic side effects, such as hair loss or severe nausea, are almost nonexistent. Because it is applied in a localized manner directly to the abdomen, systemic toxicity is minimal, which reduces toxicity to the abdomen. reduces the toxicity typical typical of conventional chemotherapy.

No. During the perfusion phase, we introduce the drugs at a strictly controlled temperature thanks to an external machine with dedicated software. This heat does not harm healthy organs, but enhances the effect of the chemotherapy selectively, destroying microscopic foci of the disease.

There are no absolute guarantees in medicine, but CRS + HIPEC is the only current treatment with curative intent for peritoneal carcinomatosis, in selected cases. While traditional chemotherapy in these stages usually has a palliative approach, we enter the operating room with the aim of achieving complete remission of the tumor. complete remission of the tumor, offering the greatest real chance of long-term survival.

Compatibility is not only defined by the name of your tumor, but also by the extent of the disease. If your primary diagnosis is ovarian, colon, stomach, appendix, rectum or peritoneum, there is a therapeutic possibility. However, being a strong candidate requires our multidisciplinary oncology committee to study your medical records, your recent radiological tests and your general condition to ensure that your body can tolerate a procedure of this magnitude with maximum benefit.

We require the exact exact details of your diagnosis. At a minimum you will need to provide: a report of your complete oncological history, high resolution radiological images (recent CT or PET-CT) and a detailed history of your previous treatments. Without this technical documentation, it is not possible to make a rigorous clinical judgment about your viability for the CRS + HIPEC.

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